Digest 6/27/23
Surveying great inventors and businesses
Axial: https://linktr.ee/axialxyz
Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio, Seranova Bio, Delix Therapeutics, Simcha Therapeutics, among others often when they are no more than an idea. We are fanatical about helping the rare inventor who is compelled to build their own enduring business. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company . We are excited to be in business with you - email us at info@axialvc.com
BioNTech:
- Founded in 2008 out of Germany by Uğur Şahin, Özlem Türeci & Christoph Huber
- Starting off with €150M in capital to develop mRNA-based individualized cancer immunotherapy
- Shifting to COVID vaccines during the pandemic
- Now going back to cancer/IO
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules led by Sigitas Mikutis from the Konstantinos Tzelepis & Gonçalo Bernardes labs https://pubs.acs.org/doi/10.1021/acscentsci.3c00015
Founder Stories: Uğur Şahin & Özlem Türeci, Building BioNTech into an Iconic Biotech Company
Presidio Medical:
- Founded in 2017 to develop a neuromodulation medical device to treat chronic pain
- Raised $72M led by Deerfield
- To conduct long-term, pivotal clinical studies of Presidio’s ultra low frequency neuromodulation (SCS) system
"The role of leaders is not to get other people to follow them but to empower others to lead."
- Bill George, former CEO of Medtronic leading it to become the market-leader it is today





