Digest 6/22/23

Surveying great inventors and businesses

Axial: https://linktr.ee/axialxyz

Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio, Seranova Bio, Delix Therapeutics, Simcha Therapeutics, among others often when they are no more than an idea. We are fanatical about helping the rare inventor who is compelled to build their own enduring business. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company . We are excited to be in business with you - email us at   info@axialvc.com

Tectonic Therapeutic:

- Founded in 2019 by Andrew Kruse & Tim Springer

- To discover antibodies targeting G-protein Coupled Receptors (GPCRs) with their GEODe platform

- Around 30% of approved drugs engaged GPCRs in some way but are still considered ‘undruggable’

Pan-KRAS inhibitor disables oncogenic signalling and tumour growth led by Dongsung Kim from the Darryl McConnell, Norbert Kraut & Piro Lito labs https://www.nature.com/articles/s41586-023-06123-3

Scientist Stories: Andrew Kruse, GPCRs & Antibody Discovery

Aledade:

- Founded in 2014 by Farzad Mostashari & Matthew Kendall

- To help physicians form/operate accountable care organizations

- Raised $260M led by Lightspeed

- Scaling its 360° practice support, workflow optimization, ACO governance & support services

"Managing is like playing the piano. Don't worry if you're not good at it at first. You'll get better as you do it more."

- Peter Gassner, Co-Founder and CEO of Veeva