Digest 6/13/23
Surveying great inventors and businesses
Axial: https://linktr.ee/axialxyz
Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio, Seranova Bio, Delix Therapeutics, Simcha Therapeutics, among others often when they are no more than an idea. We are fanatical about helping the rare inventor who is compelled to build their own enduring business. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company . We are excited to be in business with you - email us at info@axialvc.com
Revolution Medicines:
- Founded in 2014 based on the work from Martin Burke, Michael Fischbach & Kevan Shokat
- Acquiring Warp Drive Bio in 2018
- To drug RAS-driven cancers focusing on KRAS and SHP2
- With its REVBLOCKS platform, to develop small molecules“beyond rule of 5”
The Smc5/6 complex is a DNA loop-extruding motor led by Biswajit Pradhan from the Eugene Kim lab https://www.nature.com/articles/s41586-023-05963-3
Scientist Stories: Xin Jin, In Vivo Perturb-seq & Scalable Investigation of Gene Functions
Beacon Therapeutics:
- Founded in 2022, led by David Fellows (Nightstar CEO) & Nadia Waheed and Abraham Scaria, from Gyroscope & AGTC, respectively
- Raised £96M led by Syncona
- To acquire AGTC & develop gene therapies for retinal diseases
Oova Fertility:
- Founded in 2017 by Aparna Divaraniya
- Raised $10.3M led by Spero Ventures
- To commercialize a personalized fertility diagnostic device
- Measuring hormones present in women’s urine through a paper-based strip for cycle & hormone pattern management
"If it were easy, it wouldn't be as fun"
- Craig Mello, Nobel Prize winner for co-discovering RNAi
